Friday, August 24, 2001

BRIDGING - answered by NAPALM1

Q: Napalm, I saw that you are gonna be on AS till April. I am interested in staying on AS and bridging without loosing testicular function permanentaly. How do you guys cycle in clomid, hcg, tribulus with your bridging cycles? What do you tipically bridge with? I would like to start bridging but am worried about loosing testicular function(i don't mind loosing it short term, but don't wanna wind up impotent). Any info that any of you guys can provide me with on bridging info or examples is greatly appreciated. Thanks alot (BIGJOSH)

A: I bridge with primo, T3, insulin and clen. I have been doing 16 week cycles with 8 week bridges. I like the way it works out and have been pretty happy with the results. In April I am going to get completely off everything for 8 weeks and start fresh with a huge mass cycle. Well unless I place well at the Emerald cup, then I will stay on until after nationals.

Oh, I use clomid for 4 weeks after every cycle at 50/100/100/50. I don't use tribulus or HCG at all. As far as dosages its something like this:

Primo......300mg a week (all 300mg in one inj per week)
T3...........8 weeks at 25/50/75/100/100/75/50/25
slin..........25iu 3x ED before meals for 4 weeks then 25iu ED for 4 weeks
clen.........2 weeks on and 2 weeks off with ephedrine on off weeks.


Monday, August 20, 2001


Q: I'm a fighter as well as a bodybuilder. I gained 15 pounds using primobolan tabs, and I'm happy. However, next year I'll be competing in kickboxing. Can I pop one or two aggression pills before a fight? I'm normally laid back, and it's affecting my fighting instinct.

A: Before I answer your question, I'd like to tell you that this is the kind of question I really dislike. The bodybuilding subculture doesn't need any more Type A individuals acting like assholes.

Anyway, most of the benign, non-androgenic steroids have been quietly removed from the commercial market . The most plentiful steroids on the black market are the various testosterones, which are not considered anabolics but rather classic androgens.

There have always been some individuals who actually crave increased aggressiveness, and such behavior has been condoned within their peer group. The obvious examples are the overt contact sports like boxing. But football players (when they were not being tested), law enforcement personnel, and military recruits all requested androgenic steroids when I was a steroid dealer ten years ago.

As to this specific question: yes, there is such a thing as an "aggression pill." But I wonder if much of the "effects" are due to placebo. There has been a recent scientific study which validates this possibility.

The obvious choice for Kickassabol is sublingual methyltestosterone, since it's an androgen and has an activity level of only about 20 minutes. Some powerlifters I know would pop them like PEZ just before each lift.

The next choice is the trade-named Halotestin. The generic name is fluoxymesterone. In its favor (or maybe not), it's more androgenic than methyltestosterone. But it's not in sublingual form, so absorption is slow. This is avail able in Mexico as Stenox in two- milligram tabs. I could cautiously recommend 10 milligrams of this drug, but it really doesn't get into the circulation swiftly like sublingual methyltestosterone does.

The current state of the art for commercial androgens is a liquid veterinary or al preparation called Checque Drops (mibolerone). An eyedropper is included in the packaging. Checque Drops is the most androgenic substance currently being sold. It's so powerful that it's taken in micrograms, rather than the usual milligrams. It's used in animal medicine to prevent female dogs from going into heat, and it's usually added to the dog's food.

The powerlifters who use Checque Drops use two full droppers, taken orally. Although some pain-tolerant individuals do inject the liquid, which is mostly propylene glycol, a solvent, it causes tremendous burning at the injection site. It also doesn't do wonders for your stomach lining, either, which is why we have seen a limit of two droppers full.

I can't quite say if Checque Drops is terribly anabolic, because I have yet to see any powerlifter or bodybuilder use large amounts of it. However, we do know that Checque Drops will latch onto the steroid receptor tighter than even testosterone. Usually, the high-affinity androgens like dihydrotestosterone (DHT) or Proviron don't have any anabolic activity.

In the mid-'80's, the black market DDR designer steroids relabeled Checque Drops as dihydrolone and sold it as a so-called East German injectable. The chief side effect was gynecomastia. Although Checque Drops doesn't convert to estrogen, it's one of the very few steroids that cross reacts with progesterone (the other "female" hormone) receptors. It does not block the actions of progesterone but actually imparts progesterone-like activity at the receptor.

So continual use of Checque Drops may cause swelling of the (male) breast tissue, just as estrogen does. Even now, Checque Drops are used for powerlifting out-of-competition training. Within 20 minutes or so, 2 droppers of Checque Drops instill a noticeable psychological effect. So Checque Drops is my candidate for Kickassabol.

But beside s the fact that its use and possession is illegal (even if you're a horny dog), I don't recommend it because the androgens are what usually generate the side effects that lead to all the horror stories that average people associate wi th steroid use.

[pump's side note: Since this article was written, I would like to add that fina/trenbolone tends to make individuals quite aggressive.]

Q: I want to use 3 sustanon 250's a week. Should I space the shots out, or can I inject all of it at once? The sustanons are in preloaded syringes, and the needles are pretty big. How do I transfer t he contents into another syringe?

A: There is no benefit to spacing out the injections. A total oil volume of three cubic centimeters is not an especially large injection. And Sustanon, which is a blend of various durations of testosterone, is so long acting that there is no "magic" in spacing the injections throughout the week.

The standard Mexican Sustanon preload uses a 20-gauge needle. (For readers who are unfamiliar with needle sizes, the smaller the number, the bigger the needle diameter.) Most oil-based drugs are injected with a 21-gauge needle. The smaller the gauge (the higher the number), the more finger pressure needed to force the oil through the needle. In practical terms, in a standard 3-cc syringe size, most steroid users can force oil through a 23-gauge needle by pushing with one hand.

Some individuals can use a so-called vitamin needle of 25 gauge, but it entails using both hands to push the syringe plunger. Most vitamin needles do not use a screw-on connection between the needle and the syringe, and trying to force the oils through this combination generates so much fluid pressure (think of hydraulics) that usually the individual blows the syringe off the needle, and he's left with a needle sticking out of his ass, an empty syringe in his hand, and the oily steroids pewed about onto the worst of places.

When I self-surrendered to prison in 1989, I was trying to do the same vitamin needle stunt outside the prison gate inside my friend's new Mercedes and sprayed 3-ccs of Sustanon all over his beautiful Palomino leather interior.

But you're right, the 20-gauge Sustanon needle is damn big. And since you're insisting on using three preloads a week, that would create three very big holes that will accrue muscle scar tissue.

Here's how I used to do it, but first, I suppose I should give the standard warning of don't try this at home: my preference was a 23- gauge, 1-inch length. I would remove the plunger and hold it in my teeth. I held the empty syringe in my left hand, and I carefully plunged the Sustanon preload's contents into the open syringe top. I emptied two more Sustanons into the syringe, which filled it to the 3- cc limit. I then carefully and gently replaced the plunger right at the very edge of the syringe rim. I didn't want to push the plunger in too much at this point because I'd dribble steroid out of the needle end.

Once the plunger was in position, I turned the syringe upside down (plunger pointing down). I gave the syringe a few shakes downward, and that moved the trapped air up! to the needle end. At this point I could push the plunger in more, removing the air from the syringe. And then I was ready to finalize my felony.

Q: I've read that testosterone has great IGF-1 generating abilities, and Deca Durabolin is not nearly as good. Should I avoid Deca if I want to get maximum growth?

A: Testosterone is a more potent anabolic than Deca Durabolin (nandrolone decanoate). It might be that a steroid's ability to aromatize into estrogen is tied into the IGF-1 elevation. Testosterone has more conversion to estrogen than Deca Durabolin does, even though Deca Durabolin is made from an estrogen .

We know that the use of the estrogen blocker Nolvadex lowers IGF-1. And we knew years ago that something about Nolvadex was inhibiting muscle growth because I received many comments that bodybuilders grew better without Nolvadex. So should you avoid a steroid which has less side effects than testosterone in your quest for ultimate growth? It depends on how old you are.

From AIDS research, we now know that testosterone depresses the immune system. Deca Durabolin does the opposite (but not to any great degree). My recommendation is that from middle age onward (pick an age, I use age 40 as the starting point), men should use Deca Durabolin instead of testosterone, even in situations of testosterone replacement. We also should be realistic.

After a certain age, both growth and IGF-1 are not secreted at their previous youthful levels. So does it matter if Deca Durabolin reduces IGF-1 production if normal levels in middle age and onward are already insignificant?

No. Research on that question has been done. I have a feeling that IGF-1 production declines so much by middle age that its suppression from Deca Durabolin would have no effect. Another point to make about testosterone use -- we don't have a blood test that can tell us which individuals are going to lose their hair from testosterone use. I have a close friend who is 60 years old and uses 600 mg of testosterone a week and has a full head of hair. And he has been using various steroids, including testosterone, for close to 30 years.

As we can see in the professional bodybuilding ranks, some bodybuilders are losing a lot of hair to be able to compete at the over 250-pound body-weight mark. It would be interesting to interview a number of balding bodybuilders and ask them if they wished they had avoided the various baldness-causing steroids.

Is the loss of hair just a small price to pay for greatness? That probably depends on if the individual has any kind of life outside of bodybuilding. If the person's whole self and peer esteem is completely centered around his body "looking awesome," then I imagine that hair loss is no big deal.

But remember, when the person stops steroid use and muscle size decreases, the hair, of course, doesn't grow back.

Q: One of the arguments against steroid use is that all the gains I would make would disappear once I stopped using steroids. Is this true?

A: Yes, eventually, virtually all of the gains from steroid use would disappear. However, it would take years for that to happen.

This is one of the reasons football players have not been getting smaller since drug testing began . Off-season, players don't get tested, and they can accrue enough muscle mass to "coast" though the playing season. The same logic applies with drug-tested bodybuilding shows. A bodybuilder could swear on a polygraph that he hadn't used steroids for a year. Swell, except, during the year of being "clean," a good amount of steroid-generated muscle will still be there.

Steroids are still the anabolic bargain. In the studies of geriatrics using growth hormone, all of the beneficial effects induced from the growth hormone went away within a matter of weeks. I predict that the same fleeting anabolism will happen with IGF-1. Clenbuterol's effects diminished even more rapidly.

Many doctors don't want to admit it, but limited steroid use of a yearly, eight-week cycle would have virtually no adverse side effects and would probably vastly improve the health of the individual through the rest of the year. It would be interesting to put a group of bodybuilders on a mild short cycle and then track the decreases of muscle mass over the months after the end of the cycle. These results wouldn't surprise me, but I don't think the anti-steroid crowd would like to hear that steroid gains do last for a long time.

Q: I've been using some liquid GHB from two different sources. Both taste bad, but one tastes more like paint thinner than the other. The powder never tasted this bad. What gives?

A: As much as the FDA doesn't want gamma hydroxybuterate (GHB) being made, it's an absurdly simple compound to make. Just add water and lye to the lactone solvent, adjust the pH to 7, and it's done. And no, I won't give you the recipe again, and I won't tell you where to buy the lactone.

The toughest part of the granular GHB refining process was turning the liquid into a solid. The drying gets rid of all the trace solvents that impart the petrochemical smell. The various new (underground) GHB producers don't have the esoteric equipment to dry the liquid.

What is the difference between the different-tasting liquids you allegedly have? The fouler one of the two probably has a pH of slightly under seven. A well-made liquid GHB is no more toxic than the dry form. And overall, GHB has virtually no toxicity. The problem is how to know if the particular GHB is a good one.

The best you can do is scrutinize the packaging. One GHB on the black market has both contraindications and research listings included with the packaging. But don't get too worked up about GHB. It's not really an ergogenic aid. The corresponding rise of cortisol negates any positive effect caused by whatever slight growth hormone may have been caused by GHB use. GHB is a (mostly benign) recreational drug. Those who claim otherwise are just in denial.

Q: Whenever I use clenbuterol, it works great for about two weeks. After that, I can use ten tabs a day and my temperature will hardly rise. What can I do about this?

A: Clenbuterol is a beta-2 agonist. It attaches to the same receptor as your natural adrenaline and noradrenaline do. It has a very high bonding capacity to the adrenergic receptor. Whenever a drug fits well onto a cell receptor , the receptor becomes resistant to that drug. For example, the thermogenic effect of ephedrine seems to have a longer duration (though it's not as potent ) for two reasons:

1) ephedrine doesn't have a high receptor affinity.

2) ephedrine is not beta-2 specific. You might have heard about the newly discovered beta-3 receptors. The receptor is primarily a thermogenic messenger, and over half the thermogenic effect from ephedrine is from beta-3 stimulation.

Although the thermogenic message is not as intense as the beta-2 message, beta-3 receptors are very resistant to down-regulation. Clenbuterol, however, has very little beta-3 stimulation. Until some new synthetic beta-3 agonist is commercially available, the beta agonist of choice is still clenbuterol (although the stronger cimaterol is available as a research chemical in the U.S.). The rapid receptor sensitivity attenuation happens to all users, and the various dosage schemes (i.e., two days on, two days off) just aren't successful.

This attenuation and the lowering of above-normal body temperature are governed by two different mechanisms. I've written about one of them before: the shunting of T4 thyroid away from the active T3 form into the ineffective reverse-T3. Most of the thyroid in the body is the inactive T4 type. The active thyroid that actually fits onto thyroid receptors is a reduced T4, and reduced T4 occurs when one of the iodine atoms is cleaved off the molecule by a specific enzyme (deiodinase).

Since we have no way of stopping the T4 from being transformed into ineffective reverse-T3 instead of he active T3, and there's no such thing as injectable deiodinase (which would prevent the reduction), the best approach is to supplement the missing T3 with Cytomel, a synthetic T3. The trouble is, it's likely a daily amount of Cytomel higher than 25 mcg would eventually stop the production of natural thyroid stimulating hormone (TSH), and the up-regulation will take about 8 weeks.

Then, when you go off Cytomel, your body's still laggin' in production of TSH. So now you know why almost everybody who stops taking thyroid (with the exception of the drug Triacana) gets fat. For eight weeks, the body doesn't need as many calories. Up to this point, the Cytomel trick was only a partial solution.

The second and major decrease of body temperature is caused by the down- regulation of the beta-2 receptor. The receptor actually is still in the cell but not in its usual place. The receptor must be at the outside of the cell surface to be available to the beta agonist. There is research showing that the antihistamine ketotifen (trade name Zaditen by Sandoz) in large dosages will up-regulate the beta-2 receptors. This is similar to the American Periactin (cyproheptadine).

This class of antihistamine will cause drowsiness, hunger, and irritability, but you may think the negative symptoms are a small price to play.

Here are the particulars. Zaditen is only available in France in 1- mg capsules , 60 capsules to a box. It sells for 65.10 francs (about $12.25). Because of its appetite-stimulating and muscle-building properties, Zaditen is sold through some of the American AIDS buying clubs. The average price for it in America is $40 a box. The dose needed for the up-regulation of the beta-2 receptors is about 10 capsules (10 mg)--assuming you've been using 3 clenbuterol tablets (60 mcg) each day.

Sigma Chemicals, the company that has all the bodybuilding goodies that we like but can't buy (including steroids), does sell ketotifen (the fumarate version is water soluble) in raw bulk form. Keep in mind that even when used with clenbuterol, which both reduces appetite and is more of a stimulant than caffeine, Zaditen will still cause sleepiness and hunger. Those aren't nice effects, especially if you're dieting.

Your final solution to sustain clenbuterol's action is to use both Cytomel (25 mcg) and Zaditen (10 mg) each day after using clenbuterol by itself for 2 weeks . You'll need only 60 mcg of clenbuterol for a very pronounced thermogenic effect, hypothetically speaking, of course.

Q: I plan on using insulin, the Humulin R kind, and was wondering if I should take vanadyl and metformin with it ?

A: Vanadyl and metformin will affect the action of insulin in both good and bad ways. The good thing is less insulin is needed for the small amount of carbohydrates consumed. Increasing the effects of insulin at its lowest possible dosage is the ideal situation. The bad thing is that if you maintain the insulin dosage and food intake levels you had prior to adding vanadyl or metformin, you'd probably get some kind of hypoglycemic reaction, perhaps even go into a coma.

The over- the-counter insulin is enticing because it's cheap and its usefulness is supported by stories from top professional bodybuilders. The underfunded and uninformed recreational bodybuilder, however, may suffer many adverse side effects. Even at moderately low daily dosages of Humulin R, visceral (interorgan) fat will accumulate. At best, this is cosmetically repugnant (men looking pregnant). At worst, visceral fat is associated with heart disease. This fat, at least in male bodybuilders, appears to be the last fat deposit lost when dieting.

Metformin was heralded, a few years back, as an "alternative to insulin", but neither type II diabetics nor bodybuilders have been raving about this drug. What little positive effect metformin has on insulin resistance occurs only at high dosages.

We now have hopes for the next generation diabetic drug. Rezulin (troglitazone), recently available here in states. Since Rezulin's action appears to work on the insulin receptors (increasing their number) and not at the gut level like metformin, it looks like a possible bodybuilding drug. Increasing insulin receptors is a good thing, unless it happens on fat cells, too. We don't have a formula for the reduction of insulin when using these insulin synergists. Half the usual dose? Less/more ?

From my BODYOPUS experiments I've found a glucometer isn't accurate blood glucose indicator for readings under 120 dl/ml. I wouldn't try this stack. You're always cutting edge. What's the next bg thing in bodybuilding drugs ? I mean, beyond DNP and insulin, what floats your boat ? Injectable, once-a-year growth vaccasines-two are being worked on.

One vaccine inhibits somatostatin, which is a trace hormone, mostly secreted in the hypothalamus. Somatostatin is a growth-hormone- inhibiting factor, one of the counter hormones which stops the secretion of growth hormone. The other vaccine is an antigen that causes the sama anabolic response through the same receptor stimulated by clenbuterol (and other beta-agonists). Clenbuterol is anabolic in animals in only very high dosages, and these dosages would be lethal for humans. The new antigen vaccine would stimulate the same anabolic receptor, nut it wouldn't cause any of the side effects. Both of these vaccines are being developed in the beef industry in Australia.

Q: In your recent estrogen article, you mentioned Clomid (clomiphene) was safe for long-term use by bodybuilders. But in the World Anabolic Review, the authors say Clomid should be used for no more than 14 days and that it's a poor estrogen blocker. Also you gave Proviron (mesterolone) a poor mark while the World Anabolic Review claims it's one of the best estrogen blockers. What's up? I'm totally confused.

A: Although Colmid isn't the best of the anti-estrogens, it also has the dual function of mimicking luteinizing hormone, which stimulates gonadal testosterone. So, if you want to lower estrogen and raise testosterone or maintain a natural testosterone level during steroid use, Clomid, if found economically, is an attractive option.

I believe the World Anabolic Review writers probably misread the warnings about Clomid and printed the duration of use for women. There are no adverse reactions with long-term use in men that I know of. If a steroid user is looking for a pracrical estrogen blocker to prevent gynecomastia, Clomid is not the besto choice. In this case, the usual choices are either Nolvadex or Proviron. After recent discussions with one of my newsletter writers/researchers, Bill Roberts, I've come to believe Proviron might not be the terrible, androgenic steroid I always assumed it was. Bill Roberts has pointed out that the liver metabolizes Proviron into something with minimal androgenic action. Although on paper Proviron appears to be a classic androgen, its ultimate fate in the body is much more benign.